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02 / RESEARCH

NDEs & Science

Go back to the sources.
Keep the question open.

What does research say about near-death experiences? A gateway to the publications, so you can read, compare and form your own view.

From foundational work to recent research: 36 publications have been added to the 45 entries on the EMIste page ↗ and the Galileo report. Each addition links to its source and a summary in English. Last reviewed: 20 October 2026.

ARTICLES, BOOKS AND ORIGINAL SOURCES

Publications

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82 records

06 / 82

Related publication · Book

: NDEs after a suicide attempt

Sutherland, 1992

Why this related reference?

A book by Sutherland published in 1992 has been located, but no match was found for the study of 39 suicide attempts attributed to 1983. The link is a bibliographic lead, not confirmation of that statement.

Mention in EMIste: Sutherland, 1992 · timeline marker 1983.

Related reference awaiting confirmationRelated publication (new tab)
07 / 82

Related publication · Research article

: Long-term psychological effects

Gabbard & Twemlow, 1991

Why this related reference?

The article located from 1991 reexamines the role of the sense of impending death in NDEs and out-of-body experiences. It does not match a longitudinal study of 76 people conducted in 1986.

Mention in EMIste: Gabbard & Twemlow, 1991 · timeline marker 1986.

Related reference awaiting confirmationRelated publication (new tab)
09 / 82

Related publication · Book

: Observations during cardiac arrest

Sabom, 1998

Why this related reference?

The 1998 book is identifiable and presents the Atlanta Study, which began in 1994. No match has been established for either the 26 accounts or the 1990 date stated on the source page.

Mention in EMIste: Sabom, 1998 · timeline marker 1990.

Related reference awaiting confirmationRelated publication (new tab)
10 / 82

Related publication · Research article

: A typology of NDEs

Greyson, 1994

Why this related reference?

The identifiable typology dates from 1985 and is based on 89 experiences. No 1994 article matching the analysis of 73 accounts has been identified: this link is a corrected thematic match, not validation of the citation provided.

Mention in EMIste: Greyson, 1994 · timeline marker 1994.

Related reference awaiting confirmationRelated publication (new tab)
12 / 82

Related publication · Book

: Journeys and transformations

Fenwick & Fenwick, 1995

Why this related reference?

A 1995 book has been identified. Its catalog record does not confirm a longitudinal study of 379 cases conducted in 2001; the book should not be presented as that supposed article.

Mention in EMIste: Fenwick & Fenwick, 1995 · timeline marker 2001.

Related reference awaiting confirmationRelated publication (new tab)
13 / 82

Incomplete reference

: Comparisons across cultures and periods

Hall, 2010

Search details

No publication matching “Fredrich Hall” / “Hall, 2010” and this cross-cultural analysis has been identified. Without a title, journal or DOI, no publication link can reliably be provided.

Mention in EMIste: Hall, 2010 · timeline marker 2008.

Unidentified referenceNo link can be attributed with certainty
17 / 82

Incomplete reference

: Brain imaging during an NDE

Martial et al., 2017

Search details

No publication matching the claimed first imaging study has been identified. Several Martial et al. articles dated 2017 exist: one analyzes 154 accounts, another examines memory characteristics using questionnaires. They do not measure brain activation during an NDE. The untitled citation is ambiguous; the proposed links are only related work.

Mention in EMIste: Martial et al., 2017 · timeline marker 2014.

Unidentified referenceNo link can be attributed with certainty
18 / 82

Incomplete reference

: Inventory of empirical studies

Audette, 2016

Search details

No identifiable 2016 publication by John Audette matches a systematic review of more than 300 studies. Incomplete reference: do not assign it another author, title or DOI.

Mention in EMIste: Audette, 2016 · timeline marker 2016.

Unidentified referenceNo link can be attributed with certainty
19 / 82

Related publication · Book

: Accounts and cultural diversity

Long, 2010

Why this related reference?

Jeffrey Long’s 2010 book with Paul Perry is a plausible match and should be presented as a book, not a 2017 research article. The number of 39 countries and the specific description are not verified by the institutional record; the untitled citation does not allow a certain attribution.

Mention in EMIste: Long, 2010 · timeline marker 2017.

Related reference awaiting confirmationRelated publication (new tab)
20 / 82

Incomplete reference

: Transformations after an NDE

Audette et al., 2019

Search details

No 2019 systematic review is identifiable under this reference. The displayed date of 2017 also differs from the citation. Do not replace it with other authors’ work on lasting effects.

Mention in EMIste: Audette et al., 2019 · timeline marker 2017.

Unidentified referenceNo link can be attributed with certainty
21 / 82

Incomplete reference

: Review of physiological mechanisms

Greyson, 2019

Search details

Bruce Greyson’s institutional bibliography does not allow this 2019 review to be identified from the description. Work and lectures from that year exist, but are insufficient to identify the stated article. A title, journal or identifier is required.

Mention in EMIste: Greyson, 2019 · timeline marker 2019.

Unidentified referenceNo link can be attributed with certainty
22 / 82

Incomplete reference

: Neural correlates in functional MRI

Martial et al., 2020

Search details

No functional MRI study matching this description has been identified. The linked 2020 perspective article discusses NDEs as disconnected consciousness; it does not report imaging of NDEs as they occur. Do not present it as the stated study.

Mention in EMIste: Martial et al., 2020 · timeline marker 2020.

Unidentified referenceNo link can be attributed with certainty
23 / 82

Incomplete reference

: Cross-cultural comparisons

Charland-Verville et al., 2021

Search details

No 2021 cross-cultural meta-analysis attributable to Charland-Verville et al. has been identified. Similarity of themes with her other work is insufficient to establish the reference; the claimed universality should not be considered demonstrated.

Mention in EMIste: Charland-Verville et al., 2021 · timeline marker 2021.

Unidentified referenceNo link can be attributed with certainty
24 / 82

Incomplete reference

: NDEs and lucid dreams

Engmann et al., 2021

Search details

No Engmann et al. publication from 2021 matching this comparison has been identified. The survey by Kondziella, Dreier and Olsen (2019) examines the association with REM sleep intrusion using questionnaires, with no brain activity measurements or experimental comparison of lucid dreams; it is a separate related study.

Mention in EMIste: Engmann et al., 2021 · timeline marker 2021.

Unidentified referenceNo link can be attributed with certainty
25 / 82

Incomplete reference

: Psychological factors and NDE content

Zoëga et al., 2021

Search details

No publication matching Morten Zoëga / Zoëga et al. (2021) and this topic has been identified. The reference has no title, journal or identifier that would allow it to be located with certainty.

Mention in EMIste: Zoëga et al., 2021 · timeline marker 2021.

Unidentified referenceNo link can be attributed with certainty
26 / 82

Incomplete reference

: NDEs and COVID intensive care

Martial et al., 2020

Search details

No Italian study of COVID patients matching Martial et al. (2020) has been identified. The Belgian study by Rousseau et al., published in 2023, concerns 126 survivors of a prolonged intensive care stay; it should not be equated with the stated reference.

Mention in EMIste: Martial et al., 2020 · timeline marker 2021.

Unidentified referenceNo link can be attributed with certainty
27 / 82

Incomplete reference

: NDEs and premonitory dreams

Bonfioli et al., 2022

Search details

The reference could not be located with this author, date and topic. No primary article on NDEs and premonitory dreams has been identified; the link is left empty.

Mention in EMIste: Bonfioli et al., 2022 · timeline marker 2022.

Unidentified referenceNo link can be attributed with certainty
28 / 82

Incomplete reference

: NDEs and meditative states

Engmann et al., 2021

Search details

The Engmann et al. (2021) reference could not be located for a US study of NDE–meditation neural correlates. The identifiable work by Birk Engmann does not validate this description.

Mention in EMIste: Engmann et al., 2021 · timeline marker 2022.

Unidentified referenceNo link can be attributed with certainty
29 / 82

Incomplete reference

: EEG during cardiac arrest

Van den Broek et al., 2022

Search details

The Van den Broek et al. (2022) reference could not be located for an EEG study of NDEs during cardiac arrest. Author, title and journal details are insufficient to identify an article; the link is left empty.

Mention in EMIste: Van den Broek et al., 2022 · timeline marker 2022.

Unidentified referenceNo link can be attributed with certainty
30 / 82

Incomplete reference

: Meta-analysis of EEG data

Fracasso & Friedman, 2022

Search details

No Michigan EEG meta-analysis by Fracasso and Friedman from 2022 was located. A 2012 publication by these authors concerns self-reported electromagnetic effects: it does not match the description.

Mention in EMIste: Fracasso & Friedman, 2022 · timeline marker 2022.

Unidentified referenceNo link can be attributed with certainty
31 / 82

Incomplete reference

: Magnetic stimulation and perceptions

Andersen et al., 2022

Search details

No Andersen et al. (2022) article matching visual modeling of NDEs through transcranial magnetic stimulation at Imperial College was located.

Mention in EMIste: Andersen et al., 2022 · timeline marker 2022.

Unidentified referenceNo link can be attributed with certainty
32 / 82

Incomplete reference

: EEG markers and theta waves

Kondziella et al., 2023

Search details

The Kondziella et al. (2023) reference could not be located for theta EEG markers of NDEs at Max Planck. The stated date, affiliation and method are unconfirmed.

Mention in EMIste: Kondziella et al., 2023 · timeline marker 2023.

Unidentified referenceNo link can be attributed with certainty
34 / 82

Related publication · Research article

: NDEs and psychedelics

Timmermann et al., 2023

Why this related reference?

A probable match is Timmermann et al. (2018), an experimental DMT–NDE study from Imperial College and Liège. The 2023 reference and Quebec attribution are unconfirmed. Another comparison, led by Martial and coauthored by Timmermann, was published in 2024: it does not confirm the supplied citation.

Mention in EMIste: Timmermann et al., 2023 · timeline marker 2023.

Related reference awaiting confirmationRelated publication (new tab)
35 / 82

Incomplete reference

: Psychological and philosophical changes

Martial et al., 2023

Search details

No Martial et al. (2023) meta-analysis of lasting psychological and philosophical changes has been identified. Other studies of lasting effects exist, but should not be presented as this reference.

Mention in EMIste: Martial et al., 2023 · timeline marker 2023.

Unidentified referenceNo link can be attributed with certainty
36 / 82

Incomplete reference

: NDEs in palliative care

Lindstrøm et al., 2022

Search details

The Lindstrøm et al. (2022) reference could not be located for a Swedish study of NDEs in palliative care. No primary match has been identified; the link is left empty.

Mention in EMIste: Lindstrøm et al., 2022 · timeline marker 2023.

Unidentified referenceNo link can be attributed with certainty
38 / 82

Incomplete reference

: NDEs and out-of-body experiences

Kelly & Greyson, 2022

Search details

The Kelly & Greyson (2022) reference could not be located for this German neurocognitive study of out-of-body experiences. Virginia institutional publications do not confirm this author–date–method combination.

Mention in EMIste: Kelly & Greyson, 2022 · timeline marker 2023.

Unidentified referenceNo link can be attributed with certainty
39 / 82

Incomplete reference

: Psychological and neurological predispositions

Thonnard et al., 2023

Search details

The Thonnard et al. (2023) reference could not be located for a Canadian study of predispositions. The identifiable Thonnard et al. (2013) article concerns memory characteristics, in Liège, and does not match the stated topic.

Mention in EMIste: Thonnard et al., 2023 · timeline marker 2023.

Unidentified referenceNo link can be attributed with certainty
40 / 82

Incomplete reference

: Pediatric NDEs

Greyson & Liester, in preparation

Search details

Work cited as “in preparation,” without a title, protocol, journal or identifier. No matching pediatric article by Greyson and Liester has been identified; it cannot be presented as a 2024 publication.

Mention in EMIste: Greyson & Liester, in preparation · timeline marker 2024.

Unidentified referenceNo link can be attributed with certainty
41 / 82

Incomplete reference

: Multicenter study and EEG measurements

Parnia et al., 2022

Search details

Ambiguous citation: Parnia et al. (2022) corresponds to a methodological consensus statement, not an ongoing EEG study. The description evokes AWARE II, published in 2023 and conducted in the United States and the United Kingdom. Both documents are listed as leads, without declaring the source citation verified.

Mention in EMIste: Parnia et al., 2022 · timeline marker 2024.

Unidentified referenceNo link can be attributed with certainty
42 / 82

Incomplete reference

: Stability of accounts over time

van Putten et al., 2022

Search details

No van Putten et al. (2022) article or protocol matching a longitudinal comparison of NDE accounts was located. The announced 2024 launch is unverified.

Mention in EMIste: van Putten et al., 2022 · timeline marker 2024.

Unidentified referenceNo link can be attributed with certainty
43 / 82

Incomplete reference

: Methodological quality of studies

Fenwick et al., 2022

Search details

No Fenwick et al. (2022) meta-analysis matching the announced preparation in 2024 was located. Do not turn this announcement into an established publication.

Mention in EMIste: Fenwick et al., 2022 · timeline marker 2024.

Unidentified referenceNo link can be attributed with certainty
44 / 82

Incomplete reference

: East–West comparison

Wu et al., 2023

Search details

No Wu et al. (2023) article or protocol matching a Chinese–US East–West collaboration starting in 2025 was located. Do not substitute another Chinese study.

Mention in EMIste: Wu et al., 2023 · timeline marker 2025.

Unidentified referenceNo link can be attributed with certainty
45 / 82

Incomplete reference

: Memory and mental imagery

Shaw et al., 2022

Search details

No Shaw et al. (2022) article or protocol matching this British project announced for 2025 on memory–imagery networks in NDEs was located.

Mention in EMIste: Shaw et al., 2022 · timeline marker 2025.

Unidentified referenceNo link can be attributed with certainty

READ WITH DISCERNMENT

The method matters
as much as the conclusion.

How were the references verified? +

Searches by author, year and subject in publisher records, PubMed, university repositories and bibliographic catalogs. A reference is identified when the citation allows a sufficiently precise match to a book or article. This identification does not validate every claim in the original text.

How were the added studies selected? +

The selection covers foundational investigations, the main prospective studies after cardiac arrest and in intensive care, measurement tools, memory, cultural comparisons, distressing NDEs and experimental models. Recent reviews help identify gaps. The records distinguish clinical results, animal studies, isolated cases, models and recommendations. This selection of landmarks is not an exhaustive systematic review of all publications.

What does “related reference” mean? +

A publication exists on a related topic, but its date, authors or method do not allow it to be identified as the cited reference. The link is offered separately, with this discrepancy made explicit.

Why keep unidentified references? +

To make verification transparent and preserve the inventory of the original page. The absence of a match does not show that a publication does not exist. A full title, DOI or more precise bibliographic reference could help locate it.

How can the articles be accessed? +

The links lead to a publication, a PubMed record, a DOI or a publisher page. Some articles are open access; others require a subscription. A book or report is identified as such: on its own, it is not a peer-reviewed experimental study.

TWO PERSPECTIVES, ONE CURIOSITY

Studies ask questions.
Personal accounts give them a human face.

Explore personal accounts ↗
UNDERSTANDING THE RESEARCH

Neurobiological model · 1997

Ketamine as a lead for understanding NDEs

Karl L. R. Jansen

The Ketamine Model of the Near-Death Experience: A Central Role for the N-Methyl-D-Aspartate Receptor

Explore the study (new tab)

At a glance

Jansen proposes that some sensations described in NDEs could be explained by the functioning of certain brain receptors, called NMDA receptors, on which ketamine also acts.

Methodology

The article brings together observations on ketamine’s effects and knowledge about glutamate, a chemical messenger in the brain. It develops an explanatory hypothesis from this work.

Results

  • The author describes similarities between some ketamine experiences and NDE accounts.
  • He proposes that a change in NMDA receptor activity could contribute to these experiences.

What we can conclude

This is a model to be tested. A resemblance between two experiences does not show that they always have the same cause, or that this approach explains all NDEs.

Summary sources

Summary based on the article abstract published by the publisher.

Bibliographic notes

Neurobiological model article published in 1997. It is not evidence of a pilot study conducted by Jansen in 1972; that claim could not be located.

Karl L. R. Jansen · 1997 · Journal of Near-Death Studies, 16, 5–26 · DOI : 10.1023/A:1025055109480

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UNDERSTANDING THE RESEARCH

Book of personal accounts · 1975

The accounts that brought NDEs to public attention

Raymond A. Moody Jr.

Life After Life: The Investigation of a Phenomenon—Survival of Bodily Death

Explore the book (new tab)

At a glance

In Life After Life, Raymond Moody brings together accounts from people who came close to death. The book helped make the concept of the near-death experience widely known.

Methodology

The book presents and compares accounts collected after the events. The publisher’s description consulted does not provide details of recruitment or a comparison protocol.

What the book presents

  • Moody highlights similarities between the experiences recounted and proposes a vocabulary to describe them.
  • The contribution presented here is descriptive: bringing these accounts to light and opening a field of questions.

What we can conclude

These accounts document what people say they experienced. This presentation of the book cannot measure the frequency of NDEs or establish their origin.

Summary sources

Presentation of the book based on the publisher’s record; the full text was not analyzed.

Bibliographic notes

The 1975 book was identified in a library catalog. This reference is a book, not a journal article; its bibliographic identification does not validate all the methodological claims on the source page.

Raymond A. Moody Jr. · 1975 · Mockingbird Books

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UNDERSTANDING THE RESEARCH

Investigation published as a book · 1982

Examining NDE accounts in their medical context

Michael B. Sabom

Recollections of Death: A Medical Investigation

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At a glance

Cardiologist Michael Sabom examines memories reported by people who went through a critical medical situation and their connection to what happened in hospital.

Methodology

According to the book review, Sabom and Sarah Kreutziger identify patients through hospital records, then interview them about their memories. They also examine several characteristics of those interviewed.

What the book presents

  • Patients describe an impression of seeing their own body or experiences perceived as transcendent.
  • The review describes few associations with several personal characteristics studied, without providing the detailed data needed to reassess them.

What we can conclude

The investigation seeks to connect accounts with the clinical context. The available summary does not support a claim that all accounts were corroborated or a conclusion that separation between mind and brain was demonstrated.

Summary sources

Presentation based on the Kirkus review; the full text of the book was not analyzed.

Bibliographic notes

The bibliographic reference located is the book published in 1982, also cited in the following entry. The catalog confirms neither the 1978 date nor the characterization of 78 accounts as all medically corroborated.

The same book as the entry dated 1978. The statement that 102 accounts were corroborated has not been established; do not repeat it as a finding of the book.

Michael B. Sabom · 1982 · Harper & Row

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UNDERSTANDING THE RESEARCH

Interpretive article · 1976

Feeling detached from oneself in life-threatening danger

Russell Noyes Jr., Roy Kletti

Depersonalization in the Face of Life-Threatening Danger: An Interpretation

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At a glance

Noyes and Kletti explore depersonalization: the impression of feeling distant from oneself or one’s emotions when facing extreme danger.

Methodology

The authors propose a psychological and physiological interpretation of the phenomenon based on observations and earlier work. The abstract consulted does not present a new experimental trial.

Results

  • They suggest that this detachment could help maintain attention to danger while reducing an overwhelming emotion.
  • They also consider that the experience could take on spiritual meaning and be followed by a sense of renewal.

What we can conclude

This text offers a framework for interpreting experiences in the face of danger. It is insufficient to establish the cause of all NDEs or measure the frequency of these reactions.

Summary sources

Summary based on the authors’ abstract available from the publisher.

Bibliographic notes

The interpretive article appeared in 1976, not 1980. The authors also published a clinical description that year; the absence of a title on the source page leaves ambiguity between these two texts.

Russell Noyes Jr., Roy Kletti · 1976 · OMEGA—Journal of Death and Dying, 7(2), 103–114 · DOI : 10.2190/7QET-2VAU-YCDT-TJ9R

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UNDERSTANDING THE RESEARCH

Development of a measurement tool · 1983

A shared questionnaire for studying NDEs

Bruce Greyson

The Near-Death Experience Scale: Construction, Reliability, and Validity

Explore the study (new tab)

At a glance

Bruce Greyson aims to make NDE accounts comparable using a structured questionnaire rather than a simple “yes” or “no” response.

Methodology

Starting with 80 possible features, he develops a 33-question questionnaire completed for 74 experiences. Analysis of the responses identifies 16 questions and examines the score’s consistency and stability.

Results

  • The final 16-question scale shows good consistency and repeatability in the sample studied.
  • Its scores agree with another existing tool and distinguish clear NDE reports from more uncertain reports.

What we can conclude

The scale helps describe and compare reported experiences. Its score does not determine their cause or, on its own, verify what happened during unconsciousness.

Summary sources

Summary based on the authors’ abstract published in PubMed.

Bibliographic notes

Published in 1983. The abstract describes 74 experiences for the preliminary questionnaire and a final 16-item scale; the year 1988 and the figure of 67 cases are incorrect.

Bruce Greyson · 1983 · The Journal of Nervous and Mental Disease, 171(6), 369–375 · DOI : 10.1097/00005053-198306000-00007

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UNDERSTANDING THE RESEARCH

Prospective human study · 2001

What do cardiac arrest survivors report?

Pim van Lommel, Ruud van Wees, Vincent Meyers et al.

Near-Death Experience in Survivors of Cardiac Arrest: A Prospective Study in the Netherlands

Explore the study (new tab)

At a glance

Pim van Lommel’s team studies the frequency of NDEs after cardiac arrest and the changes reported in the years that follow.

Methodology

344 patients resuscitated in ten Dutch hospitals are interviewed after cardiac arrest. Their accounts are assessed using a standardized scale. Follow-up at two and eight years compares patients who reported an NDE with patients who did not.

Results

  • 62 patients, or 18%, report an experience classified as an NDE; 41, or 12% of the total, describe a more pronounced experience.
  • Follow-up describes changes in attitudes and values, greater in some respects among people who reported an NDE.

What we can conclude

The study documents memories and their impact. It cannot precisely date their formation or, on its own, establish consciousness independent of the brain.

Summary sources

Summary based on the study abstract and the author’s presentation of the protocol.

Bibliographic notes

Published in 2001. The 344 participants are survivors resuscitated after cardiac arrest; 62 (18%) reported an NDE, including 41 with a so-called core experience. These are not 344 NDEs.

Pim van Lommel, Ruud van Wees, Vincent Meyers et al. · 2001 · The Lancet, 358(9298), 2039–2045 · DOI : 10.1016/S0140-6736(01)07100-8

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UNDERSTANDING THE RESEARCH

Prospective human study · 2001

Memories after cardiac arrest

S. Parnia, D. G. Waller, R. Yeates et al.

A qualitative and quantitative study of the incidence, features and aetiology of near death experiences in cardiac arrest survivors

Explore the study (new tab)

At a glance

Sam Parnia’s team investigates how many cardiac arrest survivors retain memories of their period of unconsciousness and what those memories are like.

Methodology

Over one year, 63 survivors are interviewed within a week of cardiac arrest. Their memories are assessed with the Greyson scale and compared with medical data, including oxygenation, and religious beliefs.

Results

  • 11.1% of survivors report memories; most of these memories have NDE features and are described as pleasant.
  • Among the physiological parameters measured, only oxygen partial pressure differs: it is higher in the NDE group.

What we can conclude

Memories are uncommon in this sample. The small number of cases calls for larger studies and does not establish the cause of NDEs or the precise moment when these memories form.

Summary sources

Summary based on the authors’ abstract published in PubMed.

Bibliographic notes

The 2001 reference concerns 63 survivors, not 140. The figure of 140 corresponds to the first-stage interviews in AWARE, published in 2014; not all survivors reported an NDE. The 2010 date and description mix two publications.

S. Parnia, D. G. Waller, R. Yeates et al. · 2001 · Resuscitation · DOI : 10.1016/S0300-9572(00)00328-2

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UNDERSTANDING THE RESEARCH

Experimental animal study · 2013

A brief surge of brain activity in rats

J. Borjigin, U. Lee, T. Liu et al.

Surge of neurophysiological coherence and connectivity in the dying brain

Explore the study (new tab)

At a glance

Jimo Borjigin’s team examines the brain’s electrical activity immediately after induced cardiac arrest in rats.

Methodology

The researchers record brain activity by electroencephalogram, or EEG, during wakefulness, anesthesia and cardiac arrest. They study signal synchronization and communication between brain regions in particular.

Results

  • A transient surge of synchronized gamma waves appears within the first 30 seconds after cardiac arrest, before the electrical signal becomes almost flat.
  • Some indicators of the organization and connectivity of activity briefly increase.

What we can conclude

The rat brain can still produce organized activity at the very beginning of cardiac arrest. These measurements do not prove that the animal has an NDE and do not allow direct inferences about human experience.

Summary sources

Summary based on the abstract and results of the open-access article.

Bibliographic notes

Published in 2013. The study measures a transient surge in gamma activity and connectivity after cardiac arrest in rats; it collects no human NDE accounts and does not demonstrate conscious experience in the animals.

J. Borjigin, U. Lee, T. Liu et al. · 2013 · Proceedings of the National Academy of Sciences · DOI : 10.1073/pnas.1308285110

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UNDERSTANDING THE RESEARCH

Review article · 2005

Distinguishing brain death from states of unconsciousness

Steven Laureys

Death, unconsciousness and the brain

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At a glance

Steven Laureys explains how medical advances have changed the definition of death and why different states of unconsciousness must be distinguished.

Methodology

The article examines neurological knowledge, changing criteria for death and the associated ethical debates. It is a review, with no new group of patients recruited to measure NDEs.

Results

  • The ability to maintain some vital functions artificially has shifted attention toward neurological criteria for death.
  • Controversies remain over these definitions and their implications for care and organ donation.

What we can conclude

This review provides reference points for discussing the brain, unconsciousness and death precisely. It does not report a direct measurement of consciousness during an NDE.

Summary sources

Summary based on the author’s abstract deposited at the University of Liège.

Bibliographic notes

The identifiable reference is a 2005 review of death and states of consciousness. It is not an imaging study conducted during an NDE or a demonstration of continued consciousness during cardiac arrest.

Steven Laureys · 2005 · Nature Reviews Neuroscience · DOI : 10.1038/nrn1789

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UNDERSTANDING THE RESEARCH

Comparison of accounts · 2008

What accounts share and how they differ across cultures

John Belanti, Mahendra Perera, Karuppiah Jagadheesan

Phenomenology of near-death experiences: a cross-cultural perspective

Explore the study (new tab)

At a glance

Belanti and colleagues examine whether NDEs are recounted in the same way in different cultural settings.

Methodology

The authors compare NDE descriptions according to their experienced and recounted content. The abstract presents a comparison of accounts, without announcing a new international survey using a shared protocol.

Results

  • Some themes recur across cultures, but certain descriptions differ from typical Western European accounts.
  • The authors propose that language, religion, education and beliefs influence how the experience is interpreted and recounted.

What we can conclude

The accounts show both commonalities and diversity. This comparison demonstrates neither an identical experience everywhere nor that culture alone explains all differences.

Summary sources

Summary based on the authors’ abstract published in PubMed.

Bibliographic notes

The identifiable cross-cultural comparison article by the same authors dates from 2008, and their affiliations are Australian. It describes both shared motifs and cultural variation; no new Virginia study from 2023 has been identified.

The same identifiable cross-cultural article as the Belanti 2023 entry: published in 2008, with authors affiliated in Australia. The 2022 reference and British team are unconfirmed; probably a duplicate of entry 33.

John Belanti, Mahendra Perera, Karuppiah Jagadheesan · 2008 · Transcultural Psychiatry · DOI : 10.1177/1363461507088001

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UNDERSTANDING THE RESEARCH

Position report · 2018

Broadening the questions asked by consciousness science

Harald Walach

Beyond a Materialist Worldview — Towards an Expanded Science (Galileo Commission Report)

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At a glance

The Galileo Commission report advocates research open to conceptions of consciousness that go beyond an exclusively materialist explanation.

Methodology

Harald Walach develops a philosophical argument and discusses existing work on behalf of the Scientific and Medical Network. The report does not present a new clinical trial or a single controlled experiment.

The report’s proposals

  • It proposes broadening the hypotheses studied and examining human experiences considered difficult to explain within the framework described as dominant.
  • Its conclusions take the form of positions and research directions rather than new numerical findings.

What we can conclude

This text helps situate one strand of the debate on consciousness. Its proposals express its authors’ position and are neither a scientific consensus nor a demonstration of survival after death.

Summary sources

Summary based on the report description provided by its publishing organization.

Bibliographic notes

Report published by the Scientific and Medical Network, launched in 2018. It advocates a post-materialist expansion of science; it is a position report, distinct from a clinical study or scientific consensus. The PDF currently provided by the publisher bears a 2020 version date.

Harald Walach · 2018 · Scientific and Medical Network

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UNDERSTANDING THE RESEARCH

Investigation published as a book · 1980

Comparing accounts at the beginning of modern research

Kenneth Ring

Life at Death: A Scientific Investigation of the Near-Death Experience

Explore the book (new tab)

At a glance

Kenneth Ring presents one of the foundational investigations seeking to compare NDE accounts in a structured way.

Methodology

The book is based on interviews with 102 people who came close to death. The author develops an index to compare features of their experiences.

What the book presents

  • About half of those interviewed report a core NDE experience, according to the author’s account of his work.
  • The book helps structure the description and measurement of these experiences.

What we can conclude

This historical investigation relies on memories collected after the events. Its recruitment does not allow a frequency to be extrapolated to the whole population.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. This historical investigation relies on memories collected after the events. Its recruitment does not allow a frequency to be extrapolated to the whole population.

Kenneth Ring · 1980 · Coward, McCann & Geoghegan

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Comparative clinical study · 1986

What do children recount after a critical illness?

M. Morse, P. Castillo, D. Venecia et al.

Childhood near-death experiences

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At a glance

This pioneering study extends research to children who survived a critical illness.

Methodology

Eleven children aged 3 to 16 are interviewed after cardiac arrest or deep coma. They are compared with 29 children of similar age who received intensive care. Any memory of the period of unconsciousness is defined here as an NDE.

Results

  • Seven of the eleven children report memories, including a sense of leaving the body or passing through a tunnel.
  • None of the 29 children in the comparison group reports any memory of their period of unconsciousness.

What we can conclude

Children can report experiences similar to those of adults. The small sample and broad definition of an NDE limit comparison with current studies.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. Children can report experiences similar to those of adults. The small sample and broad definition of an NDE limit comparison with current studies.

M. Morse, P. Castillo, D. Venecia et al. · 1986 · American Journal of Diseases of Children, 140(11), 1110–1114 · DOI : 10.1001/archpedi.1986.02140250036031

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Cross-cultural investigation · 1986

Similarities and differences between Indian and American accounts

Satwant Pasricha, Ian Stevenson

Near-death experiences in India. A preliminary report

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At a glance

This early investigation broadens a then mainly Western body of accounts with testimonies collected in India.

Methodology

The authors examine sixteen Indian cases, present four accounts and compare their features with those of an earlier American sample.

Results

  • The Indian descriptions share features with the American accounts, but also show different motifs and frequencies.
  • The authors discuss the role of beliefs and cultural context in these differences.

What we can conclude

This small retrospective set allows neither a universal frequency estimate nor a conclusion that NDEs have a solely cultural cause.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. This small retrospective set allows neither a universal frequency estimate nor a conclusion that NDEs have a solely cultural cause.

Satwant Pasricha, Ian Stevenson · 1986 · The Journal of Nervous and Mental Disease, 174(3), 165–170 · DOI : 10.1097/00005053-198603000-00007

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Comparative retrospective study · 1990

Does one have to be medically close to death?

Justine E. Owens, Emily Williams Cook, Ian Stevenson

Features of "near-death experience" in relation to whether or not patients were near death

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At a glance

The authors compare medical proximity to death with the features of the experiences recounted.

Methodology

The medical records of 58 people are examined: 28 could have died without intervention and 30 were not in life-threatening danger, despite their perception of the situation.

Results

  • Both groups report related experiences.
  • Some features, including heightened perception of light and perceived cognitive abilities, are more often described in the group medically close to death.

What we can conclude

The sense of impending death must be distinguished from objectively established danger. This retrospective comparison does not determine the mechanisms of the experience.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. The sense of impending death must be distinguished from objectively established danger. This retrospective comparison does not determine the mechanisms of the experience.

Justine E. Owens, Emily Williams Cook, Ian Stevenson · 1990 · The Lancet, 336(8724), 1175–1177 · DOI : 10.1016/0140-6736(90)92780-L

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Descriptive and clinical analysis · 1992

NDEs are not always peaceful

Bruce Greyson, Nancy Evans Bush

Distressing near-death experiences

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At a glance

This foundational text draws attention to experiences perceived as terrifying or distressing.

Methodology

The authors analyze distressing accounts and propose a descriptive classification rather than a representative prevalence survey.

Results

  • Three forms are distinguished: a typical experience perceived negatively, a sense of nothingness, and scenes described as hellish.
  • The authors emphasize the possible psychological impact and the need to study it more closely.

What we can conclude

This typology brings less frequently recounted experiences to light. It establishes neither their overall frequency nor a specific cause for them.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. This typology brings less frequently recounted experiences to light. It establishes neither their overall frequency nor a specific cause for them.

Bruce Greyson, Nancy Evans Bush · 1992 · Psychiatry, 55(1), 95–110 · DOI : 10.1080/00332747.1992.11024583

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Retrospective interview investigation · 1997

How do blind people describe their perceptions?

Kenneth Ring, Sharon Cooper

Near-Death and Out-of-Body Experiences in the Blind: A Study of Apparent Eyeless Vision

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At a glance

Ring and Cooper examine accounts of NDEs and out-of-body experiences in blind people, including those blind from birth.

Methodology

The investigation includes 31 respondents and, in some cases, seeks corroborating evidence for the perceptions recounted.

Results

  • Participants describe NDEs and say they had visual impressions.
  • The authors report cases they interpret as corroborated by other information.

What we can conclude

These accounts are important to the debate on perception. A retrospective investigation without hidden targets or experimental controls does not demonstrate vision independent of the eyes or brain.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. These accounts are important to the debate on perception. A retrospective investigation without hidden targets or experimental controls does not demonstrate vision independent of the eyes or brain.

Kenneth Ring, Sharon Cooper · 1997 · Journal of Near-Death Studies, 16(2), 101–147 · DOI : 10.1023/A:1025010015662

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Retrospective comparative study · 2000

Are NDEs associated with dissociation?

Bruce Greyson

Dissociation in people who have near-death experiences: out of their bodies or out of their minds?

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At a glance

The study examines links between the depth of an NDE and dissociative symptoms.

Methodology

96 people who reported an NDE and 38 people who came close to death without an NDE complete questionnaires.

Results

  • The NDE group reports more dissociative symptoms, correlated with the depth of the experience.
  • Their level remains well below that observed in pathological dissociative disorders.

What we can conclude

The results distinguish dissociative traits from a clinical disorder. They justify neither a pathological diagnosis based solely on an NDE account nor a causal explanation.

Summary sources

Abstract and record of the original publication.

Bibliographic notes

Retrospective questionnaire study; an association does not establish that dissociation causes NDEs.

Bruce Greyson · 2000 · The Lancet, 355(9202), 460–463 · DOI : 10.1016/S0140-6736(00)82013-9

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Prospective human study · 2002

Interviewing survivors within a hospital cohort

Janet Schwaninger, Paul R. Eisenberg, Kenneth B. Schechtman et al.

A Prospective Analysis of Near-Death Experiences in Cardiac Arrest Patients

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At a glance

This US study prospectively documents the frequency and impact of NDEs after cardiac arrest.

Methodology

Cardiac arrests are monitored at one hospital from 1991 to 1994. Of 174 patients, 55 survive and 30 can be interviewed; a follow-up questionnaire explores life changes.

Results

  • Seven of the 30 people interviewed, or 23%, report an NDE associated with the cardiac arrest studied. Four others describe an earlier NDE.
  • The accounts include peace, absence of pain and detachment from the body; follow-up describes psychosocial changes.

What we can conclude

This cohort helps establish NDEs as a subject of clinical investigation. The 30 interviews and selection associated with survival do not allow a general estimate or causal explanation.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Prospective article from 2002. The journal archive also assigns it DOI 10.17514/JNDS-2002-20-4-p215-232. Seven NDEs after the cardiac arrest studied must be distinguished from four NDEs during an earlier event.

Janet Schwaninger, Paul R. Eisenberg, Kenneth B. Schechtman et al. · 2002 · Journal of Near-Death Studies, 20(4), 215–232 · DOI : 10.1023/A:1015258818660

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Clinical observation with brain stimulation · 2002

Inducing an out-of-body sensation

Olaf Blanke, Stéphanie Ortigue, Theodor Landis et al.

Stimulating illusory own-body perceptions

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At a glance

This observation examines how the brain constructs the perception of the body’s position.

Methodology

In a patient being assessed for epilepsy, the researchers electrically stimulate the right angular gyrus.

Results

  • The stimulation repeatedly produces an out-of-body sensation.
  • Other stimulations at the same site alter the perception of the limbs and bodily movement.

What we can conclude

Disrupted sensory integration can produce some aspects of an out-of-body experience. One case cannot explain all NDEs.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Neurological observation in one patient; an out-of-body sensation should not be equated with a full NDE.

Olaf Blanke, Stéphanie Ortigue, Theodor Landis et al. · 2002 · Nature, 419(6904), 269–270 · DOI : 10.1038/419269a

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Prospective human study · 2003

Are NDEs more common after cardiac arrest?

Bruce Greyson

Incidence and correlates of near-death experiences in a cardiac care unit

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At a glance

Greyson compares NDEs in patients hospitalized for different heart conditions.

Methodology

Over 30 months, 1,595 consecutive patients are assessed. Those reporting an NDE are compared with patients matched for diagnosis, age and sex.

Results

  • An NDE is reported by 10% of patients admitted after cardiac arrest, compared with 1% of other cardiac patients.
  • The groups do not differ on several measures of cognitive functioning, quality of life or cardiac severity; some attitudes toward death differ.

What we can conclude

The comparison confirms that medical settings influence the frequencies observed. It can neither date memory formation nor establish their origin.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Prospective investigation of 1,595 cardiology patients, 7% of whom were admitted after cardiac arrest. The rates of 10% and 1% correspond to two distinct clinical subgroups.

Bruce Greyson · 2003 · General Hospital Psychiatry, 25(4), 269–276 · DOI : 10.1016/S0163-8343(03)00042-2

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Comparative study using EEG and questionnaires · 2004

Looking for differences in sleep and temporal lobe activity

Willoughby B. Britton, Richard R. Bootzin

Near-Death Experiences and the Temporal Lobe

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At a glance

The authors examine temporal lobe functioning and sleep in people who reported an NDE.

Methodology

Participants are compared with controls using EEG, sleep measurements and psychological questionnaires.

Results

  • The NDE group shows more temporal epileptiform EEG activity, especially on the left.
  • Sleep differences are also observed; NDEs are not associated with more pathological stress responses.

What we can conclude

These differences suggest neurophysiological leads. They do not show that epilepsy explains NDEs or whether the observed characteristics predate the event.

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Retrospective comparative study · 2006

Exploring links with REM sleep

Kevin R. Nelson, Michelle Mattingly, Sherman A. Lee et al.

Does the arousal system contribute to near death experience?

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At a glance

The authors investigate whether phenomena usually associated with sleep are more common in people who reported an NDE.

Methodology

55 people who had an NDE are compared with controls matched for age and sex.

Results

  • Sleep paralysis and sleep-related hallucinations are more frequently reported in the NDE group.
  • The authors propose a shared predisposition involving the systems of wakefulness and REM sleep.

What we can conclude

The association supports a line of research. It does not show that REM sleep intrusion causes NDEs.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Retrospective questionnaire comparison; an association and physiological hypothesis, without a causal demonstration.

Kevin R. Nelson, Michelle Mattingly, Sherman A. Lee et al. · 2006 · Neurology, 66(7), 1003–1009 · DOI : 10.1212/01.wnl.0000204296.15607.37

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Follow-up study · 2007

Do accounts change over time?

Bruce Greyson

Consistency of near-death experience accounts over two decades: are reports embellished over time?

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At a glance

Greyson tests the idea that NDE memories become progressively embellished.

Methodology

Seventy-two people who completed the Greyson scale in the 1980s complete it again nearly twenty years later, without consulting their original answers.

Results

  • Mean scores do not change significantly, and responses at the two time points are correlated.
  • No significant relationship is found between elapsed time and score change.

What we can conclude

Scores are stable among the participants reassessed. This stability does not verify the accuracy of every detail or when the memory formed; follow-up does not cover the entire original cohort.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. Scores are stable among the participants reassessed. This stability does not verify the accuracy of every detail or when the memory formed; follow-up does not cover the entire original cohort.

Bruce Greyson · 2007 · Resuscitation, 73(3), 407–411 · DOI : 10.1016/j.resuscitation.2006.10.013

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Prospective observational study · 2010

Is CO₂ associated with NDE memories?

Zalika Klemenc-Ketis, Janko Kersnik, Stefek Grmec

The effect of carbon dioxide on near-death experiences in out-of-hospital cardiac arrest survivors: a prospective observational study

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At a glance

The team examines the link between blood gases and NDEs after out-of-hospital cardiac arrest.

Methodology

52 survivors enrolled at three Slovenian hospitals complete the Greyson scale. Their responses are compared with CO₂, oxygen and electrolyte measurements.

Results

  • Eleven patients, or 21.2%, meet the criteria for an NDE.
  • Higher CO₂ levels are associated with the presence of an NDE; some blood parameters are also linked to the intensity of the score.

What we can conclude

These data support exploring physiological mechanisms. An association in a small sample does not prove a causal mechanism or precisely locate the experience in time.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

52 out-of-hospital cardiac arrest survivors in three Slovenian hospitals; 11 NDEs identified. Associations with CO₂ are observational and do not demonstrate that this gas causes NDEs.

Zalika Klemenc-Ketis, Janko Kersnik, Stefek Grmec · 2010 · Critical Care, 14(2), R56 · DOI : 10.1186/cc8952

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Scientific review and discussion · 2011

An overview of brain-based hypotheses for discussion

Dean Mobbs, Caroline Watt

There is nothing paranormal about near-death experiences: how neuroscience can explain seeing bright lights, meeting the dead, or being convinced you are one of them

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At a glance

The authors advocate a neuroscientific interpretation of NDE components.

Methodology

They bring together research on body perception, states of consciousness and brain responses to extreme situations.

Results

  • The text proposes physiological and psychological mechanisms for several characteristic features.
  • It argues that these observations make a paranormal explanation unnecessary.

What we can conclude

This is a reasoned interpretation of existing work. It is not an experimental test of all NDEs; the 2012 commentary offers the objections for readers to consider.

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Comparison of memories · 2013

Why do these memories feel so real?

Marie Thonnard, Vanessa Charland-Verville, Serge Brédart et al.

Characteristics of Near-Death Experiences Memories as Compared to Real and Imagined Events Memories

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At a glance

This study compares the subjective richness of NDE memories with memories of experienced or imagined events.

Methodology

A memory questionnaire is administered to 21 coma survivors, including 8 with an NDE, and 18 controls.

Results

  • NDE memories contain more features than the other memories compared.
  • They are particularly rich in emotional and self-related information.

What we can conclude

Vividness distinguishes these memories in this small sample. It does not verify the external accuracy of the account or when the memory formed.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Small retrospective sample: 8 NDE memories, 13 other coma survivors and 18 controls.

Marie Thonnard, Vanessa Charland-Verville, Serge Brédart et al. · 2013 · PLOS ONE, 8(3), e57620 · DOI : 10.1371/journal.pone.0057620

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Multicenter prospective study · 2014

AWARE I: distinguishing different memories of resuscitation

Sam Parnia, Ken Spearpoint, Gabriele de Vos et al.

AWARE—AWAreness during REsuscitation—A prospective study

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At a glance

AWARE I examines memories reported after cardiac arrest and their possible correspondence with medical events.

Methodology

Over four years, 2,060 cardiac arrests are recorded. 140 survivors take part in the first interview and 101 in a second, more detailed interview.

Results

  • In the detailed interviews, 46% report memories on various themes and 9% report experiences meeting NDE criteria.
  • Two patients describe resuscitation events; one account can be compared with the timeline of care. No hidden visual target is identified.

What we can conclude

These observations justify further study of resuscitation memories. The low proportion of survivors interviewed and absence of simultaneous EEG prevent generalization or demonstration of consciousness independent of the brain.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Multicenter AWARE I study published in 2014. The percentages concern survivors interviewed, not the 2,060 cardiac arrests. The study does not provide validation through identification of a hidden visual target.

Sam Parnia, Ken Spearpoint, Gabriele de Vos et al. · 2014 · Resuscitation, 85(12), 1799–1805 · DOI : 10.1016/j.resuscitation.2014.09.004

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Comparative retrospective study · 2014

Related experiences in different situations

Vanessa Charland-Verville, Jean-Pierre Jourdan, Marie Thonnard et al.

Near-death experiences in non-life-threatening events and coma of different etiologies

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At a glance

The team compares NDE content according to context and the way accounts are collected.

Methodology

Of 190 accounts meeting Greyson criteria, 140 follow a coma and 50 an event without a threat to life. The post-anoxia group is also compared with published prospective data.

Results

  • Content and intensity do not differ significantly between the groups with and without a threat to life, or by cause of coma.
  • Retrospective data differ from prospective cohorts on several features.

What we can conclude

Medical context and recruitment method matter when interpreting results. Retrospective memories do not allow brain activity at the time of the experience to be measured.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. Medical context and recruitment method matter when interpreting results. Retrospective memories do not allow brain activity at the time of the experience to be measured.

Vanessa Charland-Verville, Jean-Pierre Jourdan, Marie Thonnard et al. · 2014 · Frontiers in Human Neuroscience, 8, 203 · DOI : 10.3389/fnhum.2014.00203

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Retrospective analysis of accounts · 2017

Do all accounts follow the same path?

Charlotte Martial, Héléna Cassol, Georgios Antonopoulos et al.

Temporality of Features in Near-Death Experience Narratives

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At a glance

The researchers study the order in which NDE features are recounted.

Methodology

Two readers analyze 154 French-language accounts meeting the Greyson scale threshold.

Results

  • Recurring features appear in the accounts.
  • Their order varies: the data do not reveal a universal sequence.

What we can conclude

This analysis describes the structure of accounts. The recounted order does not directly measure brain processes or the duration of the experience.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Analysis of 154 written accounts, without brain imaging. The August 2017 correction rectifies the name of a cited publisher and does not change the conclusions.

Charlotte Martial, Héléna Cassol, Georgios Antonopoulos et al. · 2017 · Frontiers in Human Neuroscience, 11, 311 · DOI : 10.3389/fnhum.2017.00311

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Controlled experiment in healthy volunteers · 2018

Comparing a DMT experience with NDEs

Christopher Timmermann, Leor Roseman, Luke Williams et al.

DMT Models the Near-Death Experience

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At a glance

The study examines similarities between the subjective effects of DMT and descriptions of NDEs.

Methodology

13 volunteers receive a placebo followed by DMT in separate sessions and complete the Greyson scale.

Results

  • All 13 participants exceed the usual scale threshold after DMT.
  • Many reported features overlap with those of NDEs.

What we can conclude

The overlap provides a partial experimental model. It does not demonstrate that DMT causes spontaneous NDEs.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Single-blind, fixed-order study of 13 healthy volunteers; no DMT measurements during a spontaneous NDE.

Christopher Timmermann, Leor Roseman, Luke Williams et al. · 2018 · Frontiers in Psychology, 9, 1424 · DOI : 10.3389/fpsyg.2018.01424

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Comparative analysis of accounts · 2019

Describing distressing experiences with the same tools

Helena Cassol, Charlotte Martial, Jitka Annen, Géraldine Martens, Vanessa Charland-Verville, Steve Majerus, Steven Laureys

A systematic analysis of distressing near-death experience accounts

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At a glance

The researchers compare distressing NDE accounts with more typical accounts.

Methodology

123 volunteers write their accounts and complete Greyson and memory characteristics questionnaires. Several raters classify distressing accounts.

Results

  • Seventeen accounts, or 14% of this sample, are classified as distressing: eight inverted, eight hellish and one associated with nothingness.
  • Their memories are as rich in phenomenological detail as those of typical NDEs.

What we can conclude

Distressing experiences deserve attention in their own right. Voluntary, retrospective recruitment prevents generalization of the 14% proportion to all NDEs.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. Distressing experiences deserve attention in their own right. Voluntary, retrospective recruitment prevents generalization of the 14% proportion to all NDEs.

Helena Cassol, Charlotte Martial, Jitka Annen, Géraldine Martens, Vanessa Charland-Verville, Steve Majerus, Steven Laureys · 2019 · Memory, 27(8), 1122–1129 · DOI : 10.1080/09658211.2019.1626438

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Semantic analysis of accounts · 2019

Which substance-related accounts resemble NDEs?

Charlotte Martial, Héléna Cassol, Vanessa Charland-Verville et al.

Neurochemical models of near-death experiences: A large-scale study based on the semantic similarity of written reports

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At a glance

The researchers compare the vocabulary of NDE accounts with that of experiences involving psychoactive substances.

Methodology

625 NDE accounts are compared with about 15,000 accounts involving 165 substances.

Results

  • Ketamine-related accounts show the greatest semantic similarity to NDEs.
  • Similarities also involve salvia and several psychedelics.

What we can conclude

A resemblance between texts suggests models to test. It does not establish a shared chemical mechanism.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Computational comparison of published texts; no administration of 165 substances to patients.

Charlotte Martial, Héléna Cassol, Vanessa Charland-Verville et al. · 2019 · Consciousness and Cognition, 69, 52–69 · DOI : 10.1016/j.concog.2019.01.011

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Online cross-sectional survey · 2019

Extending sleep research to an international sample

Daniel Kondziella, Jens P. Dreier, Markus Harboe Olsen

Prevalence of near-death experiences in people with and without REM sleep intrusion

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At a glance

The authors study the link between reported NDEs and REM sleep intrusion phenomena.

Methodology

1,034 adults from 35 countries complete an online survey and the Greyson scale.

Results

  • 106 participants, or about 10%, reach the scale threshold.
  • NDEs are associated with REM sleep intrusion phenomena.

What we can conclude

The study finds an association in a larger sample. Retrospective self-reports and online recruitment limit generalization and causal interpretation.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Online survey across 35 countries; the rate in this sample is not a representative worldwide estimate.

Daniel Kondziella, Jens P. Dreier, Markus Harboe Olsen · 2019 · PeerJ, 7, e7585 · DOI : 10.7717/peerj.7585

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Development and psychometric validation · 2020

A scale for describing NDEs in greater detail

Charlotte Martial, Jessica Simon, Ninon Puttaert et al.

The Near-Death Experience Content (NDE-C) scale: Development and psychometric validation

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At a glance

The researchers reassess existing tools and propose a broader measure of NDE content.

Methodology

Three studies examine the properties of the Greyson scale, then the reliability and validity of the new tool.

Results

  • The NDE-C scale has 20 questions grouped into five dimensions.
  • It shows good psychometric properties in the samples studied.

What we can conclude

The tool facilitates comparison of reported experiences. It determines neither their cause nor the external reality of their content.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

A 20-item psychometric tool that complements the Greyson scale; the score is not an objective verification of perceptions.

Charlotte Martial, Jessica Simon, Ninon Puttaert et al. · 2020 · Consciousness and Cognition, 86, 103049 · DOI : 10.1016/j.concog.2020.103049

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EEG observation of one clinical case · 2022

Observing brain activity around death

Raul Vicente, Michael Rizzuto, Can Sarica et al.

Enhanced Interplay of Neuronal Coherence and Coupling in the Dying Human Brain

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At a glance

A continuous recording allows changes in brain activity around cardiac arrest to be studied.

Methodology

The researchers analyze the EEG of an 87-year-old patient with a traumatic subdural hematoma and epileptic seizures.

Results

  • The distribution of frequencies and their coupling change around cardiac arrest.
  • Some forms of coordination persist despite the overall decline in activity.

What we can conclude

This case suggests organized activity during the end-of-life period. No memory is available to link it to an NDE or a life review.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

A single case with brain injury and epileptic seizures; the patient died, with no NDE account.

Raul Vicente, Michael Rizzuto, Can Sarica et al. · 2022 · Frontiers in Aging Neuroscience, 14, 813531 · DOI : 10.3389/fnagi.2022.813531

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Consensus statement and recommendations · 2022

Shared definitions to improve comparisons between studies

Sam Parnia, Stephen G. Post, Matthew T. Lee et al.

Guidelines and standards for the study of death and recalled experiences of death––a multidisciplinary consensus statement and proposed future directions

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At a glance

This group proposes a research framework for memories associated with cardiac arrest and resuscitation.

Methodology

The authors review the literature, definitions of death and experiences reported after coma to propose criteria and methodological directions.

Results

  • The text distinguishes several phenomena: transcendent memories, resuscitation-induced consciousness and other resuscitation experiences.
  • It proposes the term “recalled experience of death” and methods for documenting these accounts more systematically.

What we can conclude

The document helps explain the field’s terms and protocols. Its proposals express this group’s consensus; they do not demonstrate a general explanation of NDEs.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Consensus statement by a multidisciplinary group and methodological proposals. It is neither a new cohort nor a consensus demonstrating the survival of consciousness after death.

Sam Parnia, Stephen G. Post, Matthew T. Lee et al. · 2022 · Annals of the New York Academy of Sciences, 1511(1), 5–21 · DOI : 10.1111/nyas.14740

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Multicenter prospective study · 2023

AWARE II: connecting accounts with measurements during resuscitation

Sam Parnia, Tara Keshavarz Shirazi, Jignesh Patel et al.

AWAreness during REsuscitation - II: A multi-center study of consciousness and awareness in cardiac arrest

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At a glance

AWARE II combines survivor interviews, audiovisual tests and brain measurements during resuscitation.

Methodology

Across 25 centers, teams study 567 in-hospital cardiac arrests, with EEG and cerebral oxygenation measurements where possible. Of 53 survivors, 28 are interviewed.

Results

  • Eleven of the 28 people report memories or perceptions suggestive of conscious activity; six describe a transcendent experience termed RED.
  • No target image is identified; one person recognizes the auditory stimulus. Organized EEG rhythms reappear in some patients as late as 35–60 minutes into resuscitation.

What we can conclude

The findings suggest possible cognitive activity during resuscitation. Small numbers and the lack of an established individual correspondence between each account and its EEG limit conclusions about the timing and mechanism of NDEs.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

AWARE II study: 567 in-hospital cardiac arrests, 53 survivors and 28 interviews. The 11 memories/perceptions are not all NDEs: six participants report a transcendent experience termed RED. EEG signals are not a direct recording of the content of the accounts.

Sam Parnia, Tara Keshavarz Shirazi, Jignesh Patel et al. · 2023 · Resuscitation, 191, 109903 · DOI : 10.1016/j.resuscitation.2023.109903

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UNDERSTANDING THE RESEARCH

Prospective human study · 2023

Beyond cardiac arrest: memories of intensive care

Anne-Françoise Rousseau, Laurence Dams, Quentin Massart et al.

Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study

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At a glance

This Belgian cohort studies NDEs in survivors of a stay of more than seven days in intensive care.

Methodology

126 adults are interviewed after discharge from intensive care using the Greyson, dissociation and spirituality scales. Quality of life is reassessed at one year.

Results

  • Nineteen people, or 15%, meet the criteria for an NDE.
  • In the statistical model, dissociation and spirituality are the main associated factors. Among the 61 people followed up at one year, no significant association with quality of life is found.

What we can conclude

NDEs occur in different contexts of critical illness. The study does not establish their exact timing; its sample size and loss to follow-up limit conclusions about their factors and consequences.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Single-center prospective study encompassing all causes of prolonged intensive care stays: 126 enrolled, 19 NDEs. One-year follow-up covers 61 patients; this is not a cohort limited to cardiac arrests.

Anne-Françoise Rousseau, Laurence Dams, Quentin Massart et al. · 2023 · Critical Care, 27, 76 · DOI : 10.1186/s13054-023-04348-2

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UNDERSTANDING THE RESEARCH

EEG observation of four patients · 2023

Surges of activity in some patients at the end of life

Gang Xu, Temenuzhka Mihaylova, Duan Li et al.

Surge of neurophysiological coupling and connectivity of gamma oscillations in the dying human brain

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At a glance

The study looks in humans for brain phenomena previously observed in animal models.

Methodology

EEGs from four comatose patients are analyzed before and after withdrawal of ventilatory support.

Results

  • Two patients show increases in gamma activity, cross-frequency coupling and some functional connections.
  • These changes are not observed in the same way in every patient.

What we can conclude

These signals are insufficient to infer a conscious experience. As the patients died, no account is available to establish a link with an NDE.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Four comatose patients who died after ventilatory support was withdrawn; no NDE accounts available.

Gang Xu, Temenuzhka Mihaylova, Duan Li et al. · 2023 · PNAS, 120(19), e2216268120 · DOI : 10.1073/pnas.2216268120

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Syncope experiment with high-density EEG · 2024

Connecting an NDE-like experience with brain activity

Charlotte Martial, Andrea Piarulli, Olivia Gosseries et al.

EEG signature of near-death-like experiences during syncope-induced periods of unresponsiveness

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At a glance

This study compares an account collected on awakening with brain signals recorded during syncope.

Methodology

27 volunteers take part; 22 provide usable EEG recordings during periods of unresponsiveness.

Results

  • Eight volunteers report content reaching the Greyson scale threshold.
  • This group shows differences in brain activity, complexity and connectivity.

What we can conclude

The protocol provides a measurable model of an NDE-like experience. It does not reproduce all the conditions of cardiac arrest.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

Published in 2024, not 2025. Experimental syncope model in healthy volunteers, distinct from an NDE after cardiac arrest.

Charlotte Martial, Andrea Piarulli, Olivia Gosseries et al. · 2024 · NeuroImage, 298, 120759 · DOI : 10.1016/j.neuroimage.2024.120759

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UNDERSTANDING THE RESEARCH

Scoping review · 2024

Comparing what prospective cohorts can tell us

Joshua G. Kovoor, Sanjana Santhosh, Brandon Stretton et al.

Near-death experiences after cardiac arrest: a scoping review

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At a glance

This review brings together prospective studies of NDE memories after cardiac arrest.

Methodology

The authors search PubMed/MEDLINE for studies up to 23 July 2023 and include eleven studies involving interviews, following PRISMA-ScR recommendations.

Results

  • Methods, definitions and reported frequencies vary widely between studies.
  • Heterogeneity prevents a meta-analysis; only three studies follow up long-term consequences.

What we can conclude

The review confirms the existence of a clinical body of research and shows its limitations. It does not provide a single reliable frequency for all survivors or settle the origin of NDEs.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Scoping review following PRISMA-ScR, with the PubMed/MEDLINE search ending on 23 July 2023. Eleven prospective interview studies included; heterogeneity prevents meta-analysis. The published range combines varying definitions and does not give a universal NDE rate.

Joshua G. Kovoor, Sanjana Santhosh, Brandon Stretton et al. · 2024 · Discover Mental Health, 4, 19 · DOI : 10.1007/s44192-024-00072-7

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Retrospective survey with within-person comparison · 2024

Comparing two experiences lived by the same person

Charlotte Martial, Robin Carhart-Harris, Christopher Timmermann

Within-subject comparison of near-death and psychedelic experiences: acute and enduring effects

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At a glance

The study compares NDEs and psychedelic experiences within the same group of participants.

Methodology

31 adults who reported both types of experience complete several online questionnaires.

Results

  • Many mystical dimensions and lasting effects overlap.
  • NDEs involve more disembodiment; psychedelic experiences involve more visual imagery.

What we can conclude

The similarities are partial. The small volunteer sample and retrospective memories prevent a shared cause from being inferred.

Summary sources

Abstract and methodological information from the original publication.

Bibliographic notes

31 people interviewed retrospectively about two experiences; not a trial directly comparing cardiac arrest with a substance.

Charlotte Martial, Robin Carhart-Harris, Christopher Timmermann · 2024 · Neuroscience of Consciousness, 2024(1), niae033 · DOI : 10.1093/nc/niae033

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Scientific review and proposed model · 2025

An integrated model to test against the data

Charlotte Martial, Pauline Fritz, Olivia Gosseries et al.

A neuroscientific model of near-death experiences

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At a glance

The authors bring together several neuroscientific and psychological approaches to explaining NDEs.

Methodology

The review brings together research on hypoxia, neurotransmitters, the brain at the end of life and altered states of consciousness.

Results

  • The NEPTUNE model proposes a cascade of physiological and psychological processes.
  • It formulates mechanisms and predictions to test; researchers discuss its limitations in correspondence in 2026.

What we can conclude

This review provides a research framework without demonstrating that all the proposed mechanisms explain every NDE. The correspondence and replies allow readers to follow the debate.

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UNDERSTANDING THE RESEARCH

Exploratory questionnaire survey · 2025

What support do people say they need?

Marieta Pehlivanova, Katherine C. McNally, Sabina Funk, Bruce Greyson

Support Needs After a Near-Death Experience: A Quantitative Study With Experiencers

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At a glance

This study examines support sought after an NDE and its perceived usefulness.

Methodology

167 people respond to an exploratory survey about their difficulties, help-seeking and the obstacles encountered.

Results

  • 64% say they sought help; 78% consider the support they received useful.
  • A positive response when sharing and some support networks are associated with help being considered more useful.

What we can conclude

The responses shed light on integration needs. They are not a comparative trial of therapeutic effectiveness; usefulness is self-reported by participants.

Summary sources

Summary based on the cited original sources; verified on 20 October 2026.

Bibliographic notes

Publication added after verification of the bibliography. The responses shed light on integration needs. They are not a comparative trial of therapeutic effectiveness; usefulness is self-reported by participants.

Marieta Pehlivanova, Katherine C. McNally, Sabina Funk, Bruce Greyson · 2025 · Psychology of Consciousness: Theory, Research, and Practice, online publication · DOI : 10.1037/cns0000439

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Cross-sectional human study · 2026

NDEs and personal changes after intensive care for COVID-19

Amaury C. Mengin, Julie Rolling, Walid Oulehri et al.

Factors associated with post-traumatic growth in severe COVID-19 patients discharged from intensive care: the influence of near-death experiences

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At a glance

This study explores links between NDEs, memories and personal changes after severe COVID-19.

Methodology

59 survivors are assessed three months after their intensive care stay through a psychiatric interview and questionnaires on NDEs, traumatic symptoms and post-traumatic growth.

Results

  • Twelve participants, or 20.3%, meet the criteria for an NDE.
  • An NDE is associated with greater post-traumatic growth; intense memories and more traumatic symptoms are also associated with this growth.

What we can conclude

The study suggests considering the meaning given to memories during follow-up. Its small selected sample and observation at a single time point do not establish that NDEs cause these changes.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Single-center cross-sectional study published on 5 June 2026, involving 59 survivors of intensive care for COVID-19 assessed three months after their 2020 hospitalization. The association between NDEs and post-traumatic growth does not establish causation.

Amaury C. Mengin, Julie Rolling, Walid Oulehri et al. · 2026 · Scientific Reports, 16, 25655 · DOI : 10.1038/s41598-026-55687-3

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Scoping review · 2026

What intensive care research still struggles to measure

Kailai Gu, Jingying Huang, Jin Yang et al.

Near-Death Experiences in Adult ICU Patients: A Scoping Review

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At a glance

This review examines NDE experiences, associated factors, measurement tools and consequences in adults in intensive care.

Methodology

The literature search covers English- and Chinese-language publications up to 17 April 2026. Seven studies are included: five prospective cohorts, one qualitative study and one mixed-methods study.

Results

  • The studies describe multidimensional experiences and often lasting memories.
  • Psychological effects and attitudes toward death remain variable; the authors emphasize limitations of the tools and a lack of robust studies.

What we can conclude

This recent mapping helps guide support and research. The small number of studies and their differences prevent a general cause or uniform psychological effect from being inferred.

Summary sources

Authors’ abstract and cited original sources; verified on 20 October 2026.

Bibliographic notes

Scoping review published on 16 June 2026, with a literature search up to 17 April 2026. Seven studies included; the approximation of 15% cited in the introduction is not a new pooled estimate.

Kailai Gu, Jingying Huang, Jin Yang et al. · 2026 · Nursing in Critical Care, 31(4), e70532 · DOI : 10.1111/nicc.70532

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